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Endotoxin Induces Differentiated Contractile Responses in Porcine Pulmonary Arteries and Veins
Author(s) -
Björn P. Persson,
P. J. Boels,
Cecilia Lövdahl,
Patrik Rossi,
Anders Arner,
Anders Oldner
Publication year - 2010
Publication title -
journal of vascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 74
eISSN - 1423-0135
pISSN - 1018-1172
DOI - 10.1159/000319796
Subject(s) - phenylephrine , endothelin 1 , medicine , pulmonary artery , constriction , endothelin receptor , lung , endocrinology , vasoconstriction , blood vessel , circulatory system , vasodilation , anatomy , biology , receptor , blood pressure
Sepsis-induced lung injury is characterized by pulmonary hypertension, edema and deteriorated gas exchange. As in vivo studies have indicated that bacterial endotoxin predominantly induces a pulmonary venous constriction, we aimed to investigate effects of endotoxin on isolated porcine pulmonary vessels.

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