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Attempted Replication of 50 Reported Asthma Risk Genes Identifies a SNP in RAD50 as Associated with Childhood Atopic Asthma
Author(s) -
William Murk,
Kyle M. Walsh,
LingI Hsu,
Linlu Zhao,
Michael B. Bracken,
Andrew T. DeWan
Publication year - 2011
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000319536
Subject(s) - asthma , single nucleotide polymorphism , candidate gene , genome wide association study , snp , medicine , genetic association , genetics , gene , biology , genotype , immunology
Asthma is a childhood disease that is strongly influenced by genetic factors. We sought to replicate an association between single nucleotide polymorphisms (SNPs) of the top-ranked candidate genes and childhood atopic asthma in Perinatal Risk of Asthma in Infants of Asthmatic Mothers (PRAM) study subjects.

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