Amelioration of Inflammation and Cytotoxicity by Dipyridamole in Brain Endothelial Cells | Zendy

Shuzhen Guo | Zendy; Monique F. Stins | Zendy; MingMing Ning | Zendy; Eng H. Lo | Zendy

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Amelioration of Inflammation and Cytotoxicity by Dipyridamole in Brain Endothelial Cells

Author(s) -

Shuzhen Guo,

Monique F. Stins,

MingMing Ning,

Eng H. Lo

Publication year - 2010

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000319072

Subject(s) - dipyridamole , medicine , endothelial stem cell , inflammation , pharmacology , matrix metalloproteinase , zymography , tumor necrosis factor alpha , endothelium , viability assay , endocrinology , cell , biology , biochemistry , in vitro

Increasing evidence suggests that beyond its antiplatelet properties, dipyridamole may have pleiotropic effects on other cells within the neurovascular elements of the brain. In this experimental cellular study, we asked whether dipyridamole can ameliorate brain endothelial injury after exposure to inflammatory and metabolic insults.

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