Prophylactic Antibiotics Reduce Pancreatic Necrosis in Acute Necrotizing Pancreatitis: A Meta-Analysis of Randomized Trials | Zendy

Linhua Yao | Zendy; Xiayue Huang | Zendy; Yuqin Li | Zendy; Ruihua Shi | Zendy; Guoxin Zhang | Zendy

Open Access

Prophylactic Antibiotics Reduce Pancreatic Necrosis in Acute Necrotizing Pancreatitis: A Meta-Analysis of Randomized Trials

Author(s) -

Linhua Yao,

Xiayue Huang,

Yuqin Li,

Ruihua Shi,

Guoxin Zhang

Publication year - 2010

Publication title -

digestive surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.762

H-Index - 69

eISSN - 1421-9983

pISSN - 0253-4886

DOI - 10.1159/000318780

Subject(s) - medicine , randomized controlled trial , antibiotics , acute pancreatitis , meta analysis , placebo , pancreatitis , subgroup analysis , relative risk , surgery , gastroenterology , pathology , confidence interval , alternative medicine , microbiology and biotechnology , biology

The use of prophylactic antibiotics to prevent infection and reduce mortality in patients with acute necrotizing pancreatitis (ANP) remains controversial. The aim of this study is to perform a systematic review of the data from randomized controlled trials to compare prophylactic antibiotic treatment of patients with ANP versus placebo.

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