Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease | Zendy

Riika Vähätalo | Zendy; Tiina M. Asikainen | Zendy; Riitta Karikoski | Zendy; Vuokko L. Kinnula | Zendy; Carl W. White | Zendy; Sture Andersson | Zendy; Markku Heikinheimo | Zendy; Marjukka Myllärniemi | Zendy

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Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease

Author(s) -

Riika Vähätalo,

Tiina M. Asikainen,

Riitta Karikoski,

Vuokko L. Kinnula,

Carl W. White,

Sture Andersson,

Markku Heikinheimo,

Marjukka Myllärniemi

Publication year - 2010

Publication title -

neonatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.399

H-Index - 84

eISSN - 1661-7819

pISSN - 1661-7800

DOI - 10.1159/000317827

Subject(s) - transcription factor , lung disease , lung , gata transcription factor , alveolar cells , biology , disease , medicine , pathology , gene expression , gene , immunology , genetics , promoter

Premature birth and respiratory distress syndrome (RDS) are risk factors for disturbed lung development and bronchopulmonary dysplasia (BPD). The molecular mechanisms related to prematurity and BPD remain largely unknown. Epithelial expression of the transcription factor GATA-6 has been implicated in normal and abnormal murine lung development.

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