Open AccessRole of Lysyl Oxidases in Neointima Development in Vascular Allografts
Author(s) -
M. Rodríguez,
Gemma Pascual,
Alberto Cifuentes,
B. Kohler,
Juan M. Bellón,
Julia Buján
Publication year - 2010
Publication title -
journal of vascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 74
eISSN - 1423-0135
pISSN - 1018-1172
DOI - 10.1159/000317399
Subject(s) - neointima , elastin , lysyl oxidase , extracellular matrix , intimal hyperplasia , hyperplasia , medicine , restenosis , neointimal hyperplasia , elastic fiber , tunica intima , pathology , chemistry , endocrinology , biochemistry , stent , smooth muscle , carotid arteries
Extracellular matrix deposition is the main factor inducing stenotic lesions in arterial grafts. Lysyl oxidases (LOX) play a key role in stabilizing collagen and elastin.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom