Inhibition of Inducible Nitric Oxide Synthase Promotes Vein Graft Neoadventitial Inflammation and Remodelling | Zendy

Junxi Wu | Zendy; Roger M. Wadsworth | Zendy; Simon Kennedy | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Inhibition of Inducible Nitric Oxide Synthase Promotes Vein Graft Neoadventitial Inflammation and Remodelling

Author(s) -

Junxi Wu,

Roger M. Wadsworth,

Simon Kennedy

Publication year - 2010

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000316968

Subject(s) - inflammation , nitric oxide synthase , nitric oxide , neointimal hyperplasia , vascular remodelling in the embryo , intimal hyperplasia , endothelium , medicine , downregulation and upregulation , chemistry , biochemistry , restenosis , smooth muscle , stent , gene

Grafting veins into the arterial circulation causes endothelial damage and neointimal hyperplasia. However, the remodelling of vein grafts and the contribution of the endothelium is not well understood. Since nitric oxide (NO) has a crucial role in vascular function, we investigated the importance of NO synthases (NOSs) in vein graft re-endothelialization and remodelling in this study.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research