RCAN1 Regulates Vascular Branching during <i>Xenopus laevis</i> Angiogenesis
Author(s) -
Masakazu Fujiwara,
Takashi Hasebe,
Mitsuko Kajita,
Atsuko IshizuyaOka,
Mohammad Ghazizadeh,
Oichi Kawanami
Publication year - 2010
Publication title -
journal of vascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 74
eISSN - 1423-0135
pISSN - 1018-1172
DOI - 10.1159/000316873
Subject(s) - xenopus , angiogenesis , calcineurin , nfat , biology , microbiology and biotechnology , blood vessel , in vivo , signal transduction , umbilical vein , anatomy , endocrinology , medicine , in vitro , transplantation , cancer research , biochemistry , genetics , gene
The mechanisms that regulate the size-related morphologies of various blood vessels from the aorta to capillary vessels are still poorly understood. In this study, we evaluate the involvement of regulator of calcineurin 1 (RCAN1), a regulatory protein in the calcineurin/NFAT signal transduction pathway, in vascular morphology to gain further insight into these mechanisms.
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