Plant-Expressed Recombinant Mountain Cedar Allergen Jun a 1 Is Allergenic and Has Limited Pectate Lyase Activity | Zendy

Zun Liu | Zendy; Shikha Bhattacharyya | Zendy; Bo Ning | Zendy; Terumi MidoroHoriuti | Zendy; Edmund W. Czerwinski | Zendy; Randall M. Goldblum | Zendy; Andrew J. Mort | Zendy; Christopher M. Kearney | Zendy

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Plant-Expressed Recombinant Mountain Cedar Allergen Jun a 1 Is Allergenic and Has Limited Pectate Lyase Activity

Author(s) -

Zun Liu,

Shikha Bhattacharyya,

Bo Ning,

Terumi MidoroHoriuti,

Edmund W. Czerwinski,

Randall M. Goldblum,

Andrew J. Mort,

Christopher M. Kearney

Publication year - 2010

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000316345

Subject(s) - pectate lyase , allergen , recombinant dna , immunology , biology , allergy , microbiology and biotechnology , enzyme , biochemistry , gene , pectinase

Mountain cedar (Juniperus ashei) pollen commonly causes a winter time allergic rhinitis in the central USA. Jun a 1 is the dominant allergenic protein, but biologically active recombinant Jun a 1 has not been successfully expressed, despite numerous attempts with several expression systems.

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