Comparison of Multiple Steroid Concentrations in Serum and Dried Blood Spots throughout the Day of Patients with Congenital Adrenal Hyperplasia | Zendy

Kyriakie Sarafoglou | Zendy; John H. Himes | Zendy; Jean M. Lacey | Zendy; Brian C. Netzel | Zendy; Ravinder J. Singh | Zendy; Dietrich Matern | Zendy

Open Access

Comparison of Multiple Steroid Concentrations in Serum and Dried Blood Spots throughout the Day of Patients with Congenital Adrenal Hyperplasia

Author(s) -

Kyriakie Sarafoglou,

John H. Himes,

Jean M. Lacey,

Brian C. Netzel,

Ravinder J. Singh,

Dietrich Matern

Publication year - 2010

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000315910

Subject(s) - congenital adrenal hyperplasia , dried blood , androstenedione , medicine , newborn screening , endocrinology , circadian rhythm , steroid , chemistry , chromatography , androgen , pediatrics , hormone

periodic measurement of plasma concentrations of cortisol precursors on a clinic visit may be of limited value in patients with congenital adrenal hyperplasia because it does not reflect a patient's circadian patterns of adrenal steroid secretion. Steroid profiling in dried blood spots (DBS) may allow for more frequent and sensitive monitoring.

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