Transcriptomic Analysis of Mild Hypothermia-dependent Alterations During Endothelial Reperfusion Injury | Zendy

Dan Yang | Zendy; Yong Zeng | Zendy; Cui Tian | Zendy; Jing Liu | Zendy; Shubin Guo | Zendy; Yuehong Zheng | Zendy; Huihua Li | Zendy

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Transcriptomic Analysis of Mild Hypothermia-dependent Alterations During Endothelial Reperfusion Injury

Author(s) -

Dan Yang,

Yong Zeng,

Cui Tian,

Jing Liu,

Shubin Guo,

Yuehong Zheng,

Huihua Li

Publication year - 2010

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000315079

Subject(s) - kegg , biology , transcriptome , cell cycle , gene expression , microbiology and biotechnology , gene expression profiling , apoptosis , microarray analysis techniques , endothelial stem cell , gene , genetics , in vitro

Mild hypothermia (32-34 degrees C) improves resistance to ischemia-reperfusion (I/R) injury. However, the mechanisms by which it affects human cellular function are not fully elucidated. To further test for hypothermic modulation of global biological processes, we used DNA microarray technique to detect the overall gene expression profile.

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