The Non-Muscle Myosin Heavy Chain 9 Gene (MYH9) Is Not Associated with Lupus Nephritis in African Americans | Zendy

Barry I. Freedman | Zendy; Jeffrey C. Edberg | Zendy; Mary E. Comeau | Zendy; Mariana Murea | Zendy; Donald W. Bowden | Zendy; Jasmin Divers | Zendy; Graciela S. Alarcón | Zendy; Elizabeth E. Brown | Zendy; Gerald McGwin | Zendy; Jeffrey B. Kopp | Zendy; Cheryl A. Winkler | Zendy; George W. Nelson | Zendy; Gabor G. Illei | Zendy; Michelle Petri | Zendy; Rosalind RamseyGoldman | Zendy; John D. Reveille | Zendy; Luis M. Vilá | Zendy; Carl D. Langefeld | Zendy; Robert P. Kimberly | Zendy

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The Non-Muscle Myosin Heavy Chain 9 Gene <i>(MYH9)</i> Is Not Associated with Lupus Nephritis in African Americans

Author(s) -

Barry I. Freedman,

Jeffrey C. Edberg,

Mary E. Comeau,

Mariana Murea,

Donald W. Bowden,

Jasmin Divers,

Graciela S. Alarcón,

Elizabeth E. Brown,

Gerald McGwin,

Jeffrey B. Kopp,

Cheryl A. Winkler,

George W. Nelson,

Gabor G. Illei,

Michelle Petri,

Rosalind RamseyGoldman,

John D. Reveille,

Luis M. Vilá,

Carl D. Langefeld,

Robert P. Kimberly

Publication year - 2010

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000314688

Subject(s) - medicine , lupus nephritis , nephropathy , haplotype , single nucleotide polymorphism , kidney disease , gastroenterology , odds ratio , immunology , endocrinology , disease , gene , genetics , genotype , diabetes mellitus , biology

African Americans (AA) disproportionately develop lupus nephritis (LN) relative to European Americans and familial clustering supports causative genes. Since MYH9 underlies approximately 40% of end-stage renal disease (ESRD) in AA, we tested for genetic association with LN.

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