Interleukin 13 and Interleukin 4 Receptor-α Polymorphisms in Rhinitis and Asthma | Zendy

R. W. B. Bottema | Zendy; Ilja M. Nolte | Zendy; Timothy D. Howard | Zendy; Gerard H. Koppelman | Zendy; A. E. J. Dubois | Zendy; Gea de Meer | Zendy; Marjan Kerkhof | Zendy; Eugene R. Bleecker | Zendy; Deborah A. Meyers | Zendy; Dirkje S. Postma | Zendy

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Interleukin 13 and Interleukin 4 Receptor-α Polymorphisms in Rhinitis and Asthma

Author(s) -

R. W. B. Bottema,

Ilja M. Nolte,

Timothy D. Howard,

Gerard H. Koppelman,

A. E. J. Dubois,

Gea de Meer,

Marjan Kerkhof,

Eugene R. Bleecker,

Deborah A. Meyers,

Dirkje S. Postma

Publication year - 2010

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000314366

Subject(s) - asthma , immunology , proband , immunoglobulin e , medicine , interleukin 13 , interleukin , biology , genetics , gene , antibody , cytokine , mutation

Asthma and rhinitis may represent two manifestations of the same airway disease. Genetic research can increase our understanding of their common or distinct pathogenesis. IL13 and IL4R polymorphisms are associated with asthma and show gene-gene interaction in asthma. Their role in rhinitis has not been extensively studied.

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