Sensitivity to the Anorectic Effects of Leptin Is Retained in Rats Maintained on a Ketogenic Diet despite Increased Adiposity
Author(s) -
Kimberly P. Kinzig,
Mary Ann Honors,
Sara L. Hargrave,
Brandon M. Davenport,
April D. Strader,
Donna Wendt
Publication year - 2010
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000314180
Subject(s) - leptin , medicine , endocrinology , proopiomelanocortin , anorectic , hypothalamus , socs3 , arcuate nucleus , leptin receptor , chemistry , biology , obesity , food intake , cancer , suppressor
Rats maintained on a ketogenic diet (KD; 80% fat, 15% protein, 5% carbohydrate) have increased adiposity and leptin as compared to chow-fed controls (CH; 16% fat, 19% protein, 65% carbohydrate), although body weights and daily caloric intakes do not differ.
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