Cardiac Electrophysiological and Antiarrhythmic Effects of N-n-butyl Haloperidol Iodide | Zendy

Fenfei Gao | Zendy; Si-Yuan Hao | Zendy; Zhanqin Huang | Zendy; Yanmei Zhang | Zendy; Yanqiong Zhou | Zendy; Yicun Chen | Zendy; Xingping Liu | Zendy; Ganggang Shi | Zendy

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Cardiac Electrophysiological and Antiarrhythmic Effects of <i>N</i>-n-butyl Haloperidol Iodide

Author(s) -

Fenfei Gao,

Si-Yuan Hao,

Zhanqin Huang,

Yanmei Zhang,

Yanqiong Zhou,

Yicun Chen,

Xingping Liu,

Ganggang Shi

Publication year - 2010

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000303048

Subject(s) - haloperidol , medicine , electrophysiology , cardiology , cardiac electrophysiology , atrioventricular node , quinidine , pharmacology , anesthesia , tachycardia , dopamine

N-n-butyl haloperidol (F(2)), a novel compound of quaternary ammonium salt derivatives of haloperidol, was reported to antagonize myocardial ischemia/reperfusion injuries. The antiarrhythmic potential and electrophysiological effects of F(2) on rat cardiac tissues were investigated.

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