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Renal Cell Carcinoma and Proteomics
Author(s) -
Vanessa Sandim,
Denise de Abreu Pereira,
Antônio Augusto Ornellas,
Gilda Alves
Publication year - 2010
Publication title -
urologia internationalis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 53
eISSN - 1423-0399
pISSN - 0042-1138
DOI - 10.1159/000296283
Subject(s) - renal cell carcinoma , medicine , proteomics , disease , oncology , bioinformatics , biology , biochemistry , gene
Renal cell carcinoma (RCC) represents 3% of adult malignancies. About 30% of RCC patients develop metastatic disease. So far, drugs cannot significantly increase the survival of these patients. We present a recent review of proteomics and RCC. Proteomic technologies have been used in the research to discover new markers of RCC that might increase survival. Furthermore, newly discovered markers cannot increase patient survival, rather their prognostic value supporting therapeutic decisions or new agents targeted at these new markers. More research is required to develop proteomic technologies and biomarkers for identification and validation.

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