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Cholesterol and Cognitive Performance in Normal Controls and the Influence of Elective Statin Use after Conversion to Mild Cognitive Impairment: Results in a Clinical Trial Cohort
Author(s) -
David L. Sparks,
Richard J. Kryscio,
Donald J. Connor,
Marwan N. Sabbagh,
Lisa Sparks,
Yushun Lin,
Carolyn Liebsack
Publication year - 2010
Publication title -
neurodegenerative diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.98
H-Index - 57
eISSN - 1660-2862
pISSN - 1660-2854
DOI - 10.1159/000295660
Subject(s) - statin , medicine , hazard ratio , cognition , rivermead post concussion symptoms questionnaire , cholesterol , effects of sleep deprivation on cognitive performance , recall , psychology , physical therapy , psychiatry , confidence interval , cognitive psychology
We reported a significant 67% reduction in the hazard risk of incident Alzheimer's disease (AD) with elective statin use in the AD Anti-inflammatory Prevention Trial (ADAPT), without a reduction in risk of incident mild cognitive impairment (MCI).

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