Analysis of p53 and ras Gene Mutations in Endometriosis
Author(s) -
Paolo Vercellini,
Dino Trecca,
Sabina Oldani,
Nicola Stefano Fracchiolla,
Antonino Neri,
P. G. Crosignani
Publication year - 1994
Publication title -
gynecologic and obstetric investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 63
eISSN - 1423-002X
pISSN - 0378-7346
DOI - 10.1159/000292450
Subject(s) - endometriosis , exon , gene , polymerase chain reaction , tumor suppressor gene , cancer research , biology , mutation , genetics , microbiology and biotechnology , medicine , carcinogenesis , pathology
No activating mutations in codons 12, 13 and 61 of ras genes nor inactivating mutations in exons 5-9 of the p53 tumor suppressor gene were detected by polymerase chain reaction and single-strand conformation polymorphism methods in either eutopic or ectopic endometrium from 10 women with severe endometriosis.
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