Open AccessIncorporating Covariates into Multipoint Association Mapping in the Case-Parent Design
Author(s) -
Yen-Feng Chiu,
KungYee Liang,
WenHarn Pan
Publication year - 2010
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000291986
Subject(s) - covariate , locus (genetics) , genetics , allele , biology , genetic association , snp , single nucleotide polymorphism , statistics , gene , mathematics , genotype
To improve the efficiency of disease locus localization in association mapping using case-parent designs and to assess or account for the main covariate effects and gene-covariate interaction effects, while localizing the disease locus.
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