Yin Yang Haplotypes Revisited – Long, Disparate Haplotypes Observed in European Populations in Regions of Increased Homozygosity | Zendy

David Curtis | Zendy; Anna E. Vine | Zendy

Open Access

Yin Yang Haplotypes Revisited – Long, Disparate Haplotypes Observed in European Populations in Regions of Increased Homozygosity

Author(s) -

David Curtis,

Anna E. Vine

Publication year - 2010

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000289592

Subject(s) - haplotype , genetics , biology , evolutionary biology , genealogy , allele , gene , history

Yin yang haplotypes differ at every SNP. A previous study provided striking examples of these haplotypes, but claimed that their distribution across the genome could be attributed to chance. When we studied regions of homozygosity (ROHs) we found haplotypes that tended to differ at several SNPs simultaneously but did not subject this to formal testing. Here, we formally assess whether haplotypes from these regions provide evidence for the yin yang effect.

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