Early Detection of Alzheimer’s Disease with PET Imaging | Zendy

Valentina Berti | Zendy; Ricardo S. Osorio | Zendy; Lisa Mosconi | Zendy; Yi Li | Zendy; Susan De Santi | Zendy; Mony J. de Leon | Zendy

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Early Detection of Alzheimer’s Disease with PET Imaging

Author(s) -

Valentina Berti,

Ricardo S. Osorio,

Lisa Mosconi,

Yi Li,

Susan De Santi,

Mony J. de Leon

Publication year - 2010

Publication title -

neurodegenerative diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.98

H-Index - 57

eISSN - 1660-2862

pISSN - 1660-2854

DOI - 10.1159/000289222

Subject(s) - neuropathology , neuroimaging , pet imaging , medicine , neuroscience , positron emission tomography , disease , alzheimer's disease , molecular imaging , amyloid β , pathology , psychology , biology , in vivo , microbiology and biotechnology

Preclinical diagnosis of Alzheimer's disease (AD) is one of the major challenges for the prevention of AD. AD biomarkers are needed not only to reveal preclinical pathologic changes, but also to monitor progression and therapeutics. PET neuroimaging can reliably assess aspects of the molecular biology and neuropathology of AD. The aim of this article is to review the use of FDG-PET and amyloid PET imaging in the early detection of AD.

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