Epidermal Permeability Barrier Recovery Is Delayed in Vitiligo-Involved Sites
Author(s) -
J. Liu,
Wenyan Man,
Chengzhi Lv,
S.P. Song,
Yu Shi,
Peter M. Elias,
MaoQiang Man
Publication year - 2010
Publication title -
skin pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.703
H-Index - 74
eISSN - 1660-5535
pISSN - 1660-5527
DOI - 10.1159/000288166
Subject(s) - transepidermal water loss , vitiligo , barrier function , stratum corneum , erythema , dermatology , hypopigmentation , medicine , melanin , epidermis (zoology) , chemistry , pathology , biology , anatomy , biochemistry , microbiology and biotechnology
Prior studies have demonstrated that both the skin surface pH and epidermal permeability barrier function vary with skin pigmentation types. Although melanin deficiency is the main feature of vitiligo, alterations in cutaneous biophysical properties in vitiligo have not yet been well defined. In the present study, stratum corneum (SC) hydration, the skin surface pH and epidermal permeability barrier function in vitiligo were evaluated.
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