Enhanced Absorption through Damaged Skin: An Overview of the in vitro Human Model | Zendy

Shilpa Gattu | Zendy; Howard I. Maïbach | Zendy

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Enhanced Absorption through Damaged Skin: An Overview of the in vitro Human Model

Author(s) -

Shilpa Gattu,

Howard I. Maïbach

Publication year - 2010

Publication title -

skin pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.703

H-Index - 74

eISSN - 1660-5535

pISSN - 1660-5527

DOI - 10.1159/000288163

Subject(s) - absorption (acoustics) , human skin , in vivo , in vitro , pharmacology , chemistry , medicine , dermatology , biology , biochemistry , materials science , microbiology and biotechnology , genetics , composite material

Quantifying percutaneous absorption of topical drugs as well as those compounds relevant to occupational exposure is important for assessing delivery, efficacy and toxicology. Methods for assessing absorption are established for intact skin; however, what may be equally relevant is how much absorption occurs through damaged skin.

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