Mechanical Stress Modulates SOCS-1 Expression in Human Vascular Smooth Muscle Cells | Zendy

Marc Dangers | Zendy; Yulia Kiyan | Zendy; Karsten Grote | Zendy; Bernhard Schieffer | Zendy; Hermann Haller | Zendy; Inna Dumler | Zendy

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Mechanical Stress Modulates SOCS-1 Expression in Human Vascular Smooth Muscle Cells

Author(s) -

Marc Dangers,

Yulia Kiyan,

Karsten Grote,

Bernhard Schieffer,

Hermann Haller,

Inna Dumler

Publication year - 2010

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000281583

Subject(s) - urokinase receptor , downregulation and upregulation , gene silencing , vascular smooth muscle , focal adhesion , microbiology and biotechnology , integrin , ubiquitin ligase , signal transduction , receptor , biology , chemistry , cancer research , ubiquitin , endocrinology , biochemistry , smooth muscle , gene

The growth-promoting effect of mechanical stress on vascular smooth muscle cells (VSMC) has been implicated in the progress of cardiovascular diseases related to elevated blood pressure. The underlying molecular mechanisms are, however, not completely defined.

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