Can a Cure Be Achieved with Taxane-Based Chemotherapy plus Surgery in Patients with Primary Mediastinal Non-Seminomatous Germ Cell Tumors and Progression or Relapse Despite First-Line Chemotherapy? | Zendy

Věra Miškovská | Zendy; Antonin Lévy | Zendy; Christophe C. Massard | Zendy; Marine GrossGoupil | Zendy; Alberto Bossi | Zendy; Karim Fizazi | Zendy

Open Access

Can a Cure Be Achieved with Taxane-Based Chemotherapy plus Surgery in Patients with Primary Mediastinal Non-Seminomatous Germ Cell Tumors and Progression or Relapse Despite First-Line Chemotherapy?

Author(s) -

Věra Miškovská,

Antonin Lévy,

Christophe C. Massard,

Marine GrossGoupil,

Alberto Bossi,

Karim Fizazi

Publication year - 2010

Publication title -

onkologie

Language(s) - English

Resource type - Journals

eISSN - 1423-0240

pISSN - 0378-584X

DOI - 10.1159/000277824

Subject(s) - taxane , chemotherapy , germ cell tumors , medicine , oncology , germ cell , surgery , cancer , biology , breast cancer , biochemistry , gene

Primary mediastinal non-seminomatous germ cell tumors (NSCGTs) have a poor prognosis in the International Germ Cell Cancer Collaborative Group (IGCCCG) classification. There is no clear standard of treatment at relapse. Between 1995 and 2005, 13 patients experienced progression or relapse, and 1 patient was cured with a taxane-based chemotherapy plus surgical resection at our institution.

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