Gap Junction Channel Modulates Pulmonary Vascular Permeability through Calcium in Acute Lung Injury: An Experimental Study | Zendy

Jinzhou Zhang | Zendy; Wen Wang | Zendy; Jing Sun | Zendy; Qiang Li | Zendy; Jincheng Liu | Zendy; Hailong Zhu | Zendy; Tao Chen | Zendy; Hongbing Wang | Zendy; Shiqiang Yu | Zendy; Guocheng Sun | Zendy; Wensheng Chen | Zendy; Dinghua Yi | Zendy

Open Access

Gap Junction Channel Modulates Pulmonary Vascular Permeability through Calcium in Acute Lung Injury: An Experimental Study

Author(s) -

Jinzhou Zhang,

Wen Wang,

Jing Sun,

Qiang Li,

Jincheng Liu,

Hailong Zhu,

Tao Chen,

Hongbing Wang,

Shiqiang Yu,

Guocheng Sun,

Wensheng Chen,

Dinghua Yi

Publication year - 2010

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000274384

Subject(s) - evans blue , medicine , calcium channel blocker , channel blocker , calcium in biology , gap junction , lung , endocrinology , intracellular , vascular permeability , calcium , permeability (electromagnetism) , connexin , chemistry , biochemistry , membrane

Increased pulmonary vascular permeability is a hallmark of acute lung injury (ALI). Gap junction channels (GJCs) connect adjacent cells and facilitate ion exchange. It remained unclear whether GJCs modulate pulmonary permeability in ALI through intracellular calcium.

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