Open AccessHMGB1 Attenuates Anti-Metastatic Defense of the Lymph Nodes in Colorectal Cancer
Author(s) -
Yukiko Moriwaka,
Yi Luo,
Hitoshi Ohmori,
Kiyomu Fujii,
Naokuni Tatsumoto,
Tomonori Sasahira,
Hiroki Kuniyasu
Publication year - 2010
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000272950
Subject(s) - lymph , hmgb1 , colorectal cancer , medicine , metastasis , immune system , macrophage , lymph node , cancer , cancer research , pathology , immunology , inflammation , biology , in vitro , biochemistry
Cancer-secreted high mobility group 1 (HMGB1) induces apoptosis of macrophages and suppresses the host anti-cancer immune system.
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