Identification of a ‘Snapshot’ of Co-Expressed Angiogenic Markers in Laser-Dissected Vessels from Unstable Carotid Plaques with Targeted Arrays | Zendy

Mark Slevin | Zendy; Marta Miguel Turu | Zendy; Norma Rovira | Zendy; Ana Luque | Zendy; Maribel Baldellou | Zendy; Jerzy Krupiński | Zendy; Lina Badimón | Zendy

Open Access

Identification of a ‘Snapshot’ of Co-Expressed Angiogenic Markers in Laser-Dissected Vessels from Unstable Carotid Plaques with Targeted Arrays

Author(s) -

Mark Slevin,

Marta Miguel Turu,

Norma Rovira,

Ana Luque,

Maribel Baldellou,

Jerzy Krupiński,

Lina Badimón

Publication year - 2009

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000265566

Subject(s) - angiogenesis , laser capture microdissection , endoglin , pathology , extracellular matrix , vasa vasorum , blood vessel , neovascularization , fibulin , adventitia , medicine , cancer research , biology , microbiology and biotechnology , gene expression , gene , biochemistry , stem cell , cd34

Angiogenesis is a feature of the atherogenic process, with intimal neovascularisation arising from vessels in the adventitia, adjacent to a plaque. Immature, leaky blood vessels from unstable plaques proliferate abnormally and, being poorly invested with smooth muscle cells, may contribute to instability of the plaque by facilitation of inflammatory cell infiltration and haemorrhagic complications.

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