Open AccessLow Erythropoietin Plasma Levels during Exacerbations of COPD
Author(s) -
Ernest Sala,
Catalina Balaguer,
Cristina Villena,
Ángel Ríos,
Aioguera,
Belén Núñez,
Àlvar Agustí
Publication year - 2009
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000264604
Subject(s) - medicine , copd , erythropoietin , exacerbation , gastroenterology , lung , lung function , immunology
It is known that pro-inflammatory cytokines suppress in vitro the gene expression and protein production of erythropoietin (Epo). We hypothesized that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) may influence Epo production, particularly during episodes of exacerbation of the disease (ECOPD) where an inflammatory burst is known to occur.
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