Newcastle Disease Virus Infection Promotes Bax Redistribution to Mitochondria and Cell Death in HeLa Cells
Author(s) -
Aidin Molouki,
YiTe Hsu,
Fatemeh Jahanshiri,
Rozita Rosli,
Khatijah Yusoff
Publication year - 2009
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000264198
Subject(s) - apoptosis , hela , cytoplasm , newcastle disease , mitochondrion , virus , biology , virology , programmed cell death , cancer cell , microbiology and biotechnology , cytochrome c , cell , cancer , biochemistry , genetics
Newcastle disease virus (NDV) is an avian paramyxovirus that has gained a lot of interest in cancer viro-therapeutic applications because of its ability to selectively induce apoptosis in human cancer cells. However, the underlying mechanisms by which NDV induces apoptosis in human cancer cells are still not entirely understood.
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