The Toll-Like Receptor 4 D299G and T399I Polymorphisms Are Associated with Crohn’s Disease and Ulcerative Colitis: A Meta-Analysis
Author(s) -
Xiu-yun Shen,
Ruihua Shi,
Hongjie Zhang,
Kebei Li,
Yang Zhao,
Ruyang Zhang
Publication year - 2010
Publication title -
digestion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.882
H-Index - 75
eISSN - 1421-9867
pISSN - 0012-2823
DOI - 10.1159/000260417
Subject(s) - ulcerative colitis , medicine , gastroenterology , crohn's disease , allele , population , inflammatory bowel disease , immunology , genotype , disease , biology , gene , genetics , environmental health
Some studies have reported that Toll-like receptor 4 (TLR4) D299G and T399I polymorphisms are associated with increased Crohn's disease (CD) and ulcerative colitis (UC) risk in the Caucasian population. However, the results have been inconsistent.
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