Localization of DNA and RNA in Eosinophil Secretory Granules
Author(s) -
Ali R. Behzad,
David C. Walker,
Thomas Abraham,
John E. McDonough,
Salahadin Mahmudi-Azer,
Fanny Chu,
Furquan Shaheen,
James C. Hogg,
Peter D. Paré
Publication year - 2009
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000260079
Subject(s) - immunogold labelling , rna , biology , microbiology and biotechnology , eosinophil , eosinophil cationic protein , dna , staining , antibody , immunology , biochemistry , gene , asthma , genetics
Although the accepted paradigm is that the proteins stored in eosinophil crystalloid granules are translated from messenger RNA transcribed in the cell nucleus, recent ultrastructural evidence suggests that protein synthesis may also take place within eosinophilic granules.
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