Ghrelin Receptor Expression in Lymphocytes Isolated from Adult Cystic Fibrosis Patients | Zendy

Rubin I. Cohen | Zendy; Subani Chandra | Zendy; Seth Koenig | Zendy; Donna Tsang | Zendy; Darrell M. Wilson | Zendy; Thomas W. McCloskey | Zendy

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Ghrelin Receptor Expression in Lymphocytes Isolated from Adult Cystic Fibrosis Patients

Author(s) -

Rubin I. Cohen,

Subani Chandra,

Seth Koenig,

Donna Tsang,

Darrell M. Wilson,

Thomas W. McCloskey

Publication year - 2009

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000254486

Subject(s) - ghrelin , medicine , endocrinology , receptor expression , receptor , appetite , cachexia , exacerbation , weight loss , obesity , cancer

To explore mechanisms of weight loss in cystic fibrosis (CF), we studied ghrelin receptor expression on isolated lymphocytes from CF subjects with different body mass indices (BMIs). Eating behavior is influenced by hormone peptides such as ghrelin, a potent appetite stimulator. However, studies on ghrelin plasma levels in CF showed it to be increased in cachectic subjects, the expected physiological response.

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