Disseminated Reticulate Hypomelanosis Developing during Primary Biliary Cirrhosis | Zendy

R. Viraben | Zendy; B. Couret | Zendy; B Gorguet | Zendy

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Disseminated Reticulate Hypomelanosis Developing during Primary Biliary Cirrhosis

Author(s) -

R. Viraben,

B. Couret,

B Gorguet

Publication year - 1997

Publication title -

dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.224

H-Index - 92

eISSN - 1421-9832

pISSN - 1018-8665

DOI - 10.1159/000245993

Subject(s) - primary biliary cirrhosis , reticulate , pathology , dermatology , histopathological examination , medicine , biology , immunology , botany

We report on a 50-year-old woman with disseminated reticulate hypomelanosis developing on the limbs and abdomen during primary biliary cirrhosis (PBC). Histopathological examination showed vacuolar basal cells, dyskeratosis and large multinucleated epidermal cells. Diagnosis of lichen sclerosus et atrophicus and autoimmune disease are discussed. The similarity between cutaneous changes in PBC and a graft-versus-host reaction is outlined.

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