Phosphorylation Status of Fas-Associated Death Domain-Containing Protein Regulates Telomerase Activity and Strongly Correlates with Prostate Cancer Outcomes | Zendy

Yoshiaki Matsumura | Zendy; Keiji Shimada | Zendy; Nobumichi Tanaka | Zendy; Kiyohide Fujimoto | Zendy; Yoshihiko Hirao | Zendy; Noboru Konishi | Zendy

Open Access

Phosphorylation Status of Fas-Associated Death Domain-Containing Protein Regulates Telomerase Activity and Strongly Correlates with Prostate Cancer Outcomes

Author(s) -

Yoshiaki Matsumura,

Keiji Shimada,

Nobumichi Tanaka,

Kiyohide Fujimoto,

Yoshihiko Hirao,

Noboru Konishi

Publication year - 2009

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000245895

Subject(s) - fadd , telomerase , prostate cancer , telomerase reverse transcriptase , cancer research , death domain , cancer , biology , medicine , programmed cell death , apoptosis , caspase , biochemistry , gene

We investigated whether the phosphorylated Fas-associated death domain protein (FADD) at serine 194 regulated human telomerase reverse transcriptase (hTERT) expression, telomerase activity and cancer progression using prostate cancer cell lines and radical prostatectomy samples taken from patients receiving neoadjuvant hormonal therapy (NHT).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research