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Genome-Wide Analysis of Histone H3 Lysine 4 Trimethylation in Peripheral Blood Mononuclear Cells of Minimal Change Nephrotic Syndrome Patients
Author(s) -
Li Zhang,
Yong Dai,
Wujian Peng,
Juanjuan Lu,
Yanliang Zhang,
Linxian Wang
Publication year - 2009
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000243811
Subject(s) - h3k4me3 , epigenome , dna methylation , histone h3 , epigenetics , peripheral blood mononuclear cell , histone , microbiology and biotechnology , medicine , real time polymerase chain reaction , microarray , microarray analysis techniques , chromatin immunoprecipitation , biology , immunology , gene expression , cancer research , endocrinology , promoter , gene , genetics , in vitro
Studies of the epigenome have attracted some interest in nephrology. However, to date, our knowledge about the alterations in histone modification in minimal change nephrotic syndrome (MCNS) is unknown. This study aimed to investigate the variations in histone H3 lysine 4 trimethylation (H3K4me3) in peripheral blood mononuclear cells of patients with MCNS.

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