Mast Cells Induce Migration of Dendritic Cells in a Murine Model of Acute Allergic Airway Disease | Zendy

Sebastian Reuter | Zendy; Nina Dehzad | Zendy; Helen Martin | Zendy; A Heinz | Zendy; Timo Castor | Zendy; Stephan Sudowe | Zendy; Angelika B. ReskeKunz | Zendy; Michael Stassen | Zendy; Roland Buhl | Zendy; Christian Taube | Zendy

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Mast Cells Induce Migration of Dendritic Cells in a Murine Model of Acute Allergic Airway Disease

Author(s) -

Sebastian Reuter,

Nina Dehzad,

Helen Martin,

A Heinz,

Timo Castor,

Stephan Sudowe,

Angelika B. ReskeKunz,

Michael Stassen,

Roland Buhl,

Christian Taube

Publication year - 2009

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000242359

Subject(s) - immunology , mast cell , sensitization , dendritic cell , lymph , chemistry , medicine , microbiology and biotechnology , immune system , biology , pathology

The migration of dendritic cells (DCs) from the lungs to the regional lymph nodes is necessary for the development of allergic airway disease. Following activation, mast cells release a variety of stored or de novo-produced inflammatory mediators, several of them being capable of activating DCs. In this study, the role of mast cells on DC migration from the lungs to the thoracic lymph nodes was investigated in sensitized mice.

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