Effectiveness of Donepezil in Reducing Clinical Worsening in Patients with Mild-to-Moderate Alzheimer’s Disease
Author(s) -
David Wilkinson,
Rachel Schindler,
Elias Schwam,
Gunhild Waldemar,
Roy Jones,
Serge Gauthier,
Oscar L. López,
Jeffrey L. Cummings,
Yikang Xu,
Howard Feldman
Publication year - 2009
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000241877
Subject(s) - donepezil , placebo , clinical global impression , medicine , population , odds ratio , alzheimer's disease , clinical trial , cognition , dementia , psychology , disease , psychiatry , pathology , alternative medicine , environmental health
Therapeutic endpoints based on reduced clinical worsening represent clinically relevant and realistic goals for patients suffering from progressive neurodegenerative disorders such as Alzheimer's disease (AD).
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