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Combination of Captopril and Allopurinol Retards Fructose-Induced Metabolic Syndrome
Author(s) -
Carmen Roncal,
Sirirat Reungjui,
Laura Gabriela SánchezLozada,
Wei Mu,
Yuri Y. Sautin,
Takahiko Nakagawa,
Richard J. Johnson
Publication year - 2009
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000235731
Subject(s) - medicine , allopurinol , metabolic syndrome , endocrinology , hyperuricemia , insulin resistance , fenofibrate , dyslipidemia , hypertriglyceridemia , hyperinsulinemia , captopril , fructose , type 2 diabetes , diabetes mellitus , blood pressure , uric acid , cholesterol , triglyceride , biology , biochemistry
Both ACE inhibitors and allopurinol have been shown to partially prevent metabolic syndrome induced by fructose. We tested the hypothesis that combined therapy might be more effective at blocking the metabolic syndrome induced with fructose.

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