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Polymorphisms of <i>PHF11</i> and <i>DPP10 </i> Are Associated with Asthma and Related Traits in a Chinese Population
Author(s) -
Jinming Gao,
Weijuan Li,
Saffron A.G. WillisOwen,
Lei Jiang,
Yiyi Ma,
Xinlun Tian,
Miriam F. Moffatt,
William Cookson,
Yaoguang Lin,
Youming Zhang
Publication year - 2009
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000235545
Subject(s) - haplotype , asthma , linkage disequilibrium , odds ratio , medicine , genetics , genetic association , candidate gene , population , immunology , single nucleotide polymorphism , genotype , biology , gene , environmental health
Initial studies by positional cloning have identified the genes encoding the plant homeodomain zinc finger protein 11 (PHF11) and dipeptidyl-peptidase 10 (DPP10) as asthma susceptibility genes. The variants in the two genes have been associated with asthma in several populations of European or Latin American origin.

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