Impact of Depression on Diabetes mellitus

The consideration of the interaction of psychological factors like distress and depression with human behavior has led to a better understanding of pathophysiology and treatment of chronic diseases. Stress factors associated with distress and depression relate to a loss of treatment adherence and compliance with consecutive rise in addictive behavior and accompanying complications [1], thus increasing the need of complex approaches to the treatment of those diseases. Depression is common in patients with diabetes mellitus [2]. The prevalence of any depression (major or minor forms) is significantly higher in patients with type 2 diabetes mellitus (T2DM) than in those without diabetes (17.6 vs. 9.8%) [3]. Depression has been shown to be associated to treatment non-adherence [4].