Increased Frequency of High Serum IgM among Mothers of Infants with Neonatal Group-B Streptococcal Septicemia | Zendy

Å.K. Rundgren | Zendy; Karen Kvist Christensen | Zendy; Poul Christensen | Zendy

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Increased Frequency of High Serum IgM among Mothers of Infants with Neonatal Group-B Streptococcal Septicemia

Author(s) -

Å.K. Rundgren,

Karen Kvist Christensen,

Poul Christensen

Publication year - 1985

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000233847

Subject(s) - group b , immunology , meningitis , medicine , streptococcus agalactiae , group a , immunoglobulin m , streptococcus , immunoglobulin g , antibody , pediatrics , biology , bacteria , genetics

Total serum IgM levels were studied in 84 mothers of infants with group-B streptococcal (GBS) septicemia/meningitis and compared to IgM concentrations in 91 parturients who were urogenital carriers of GBS but nevertheless gave birth to healthy infants. In all, 22 (27%) in the study group showed IgM levels above the arbitrarily selected limit of 2.40 g/l, in contrast to 12 (13%) of 91 controls (p = 0.02). Among the study group members whose infants were infected with GBS type III, 8 of 34 (24%) were high in serum IgM, compared to only 2 of 34 (6%) of the corresponding controls (p = 0.04). The total serum IgG levels did not differ between the two groups.

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