The Role of IgG4 as Blocking Antibodies in Asthmatics and in Bee Keepers | Zendy

Takemasa Nakagawa | Zendy; Terumasa Miyamoto | Zendy

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The Role of IgG4 as Blocking Antibodies in Asthmatics and in Bee Keepers

Author(s) -

Takemasa Nakagawa,

Terumasa Miyamoto

Publication year - 1985

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000233787

Subject(s) - immunology , blocking antibody , medicine , antibody , allergen , radioimmunoassay , blocking (statistics) , antigen , allergy , statistics , mathematics

Sera from 40 asthmatic patients and from 77 bee keepers were evaluated by solid-phase radioimmunoassay for their allergen-specific IgG4 antibody levels. The results indicated that allergen-specific IgG4 antibodies become prominent upon repeated parenteral stimulation with antigen, i.e. immunotherapy and bee stings, and suggested the possible association of IgG4 with blocking antibodies in these allergic conditions.

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