The Anti-Allergic Effects of FPL 52694 | Zendy

Edward Wells | Zendy; R P Eady | Zendy; S.T. Harper | Zendy; M.E. Mather | Zendy; Patricia A. Riley | Zendy

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The Anti-Allergic Effects of FPL 52694

Author(s) -

Edward Wells,

R P Eady,

S.T. Harper,

M.E. Mather,

Patricia A. Riley

Publication year - 1985

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000233689

Subject(s) - sodium cromoglycate , disodium cromoglycate , chromone , cromolyn sodium , immunoglobulin e , immunology , chemistry , nedocromil sodium , pharmacology , allergic reaction , medicine , allergy , asthma , stereochemistry , antibody , pathology , alternative medicine , placebo

The substituted chromone carboxylic acid FPL 52694 inhibited models of IgE-mediated immediate hypersensitivity reactions in the rat by a mechanism similar to that of sodium cromoglycate. The compound was more potent than sodium cromoglycate but unlike cromoglycate was active following oral administration.

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