Role of Cytokines in the Pathophysiology of Acute-on-Chronic Liver Failure
Author(s) -
Qing Liu
Publication year - 2009
Publication title -
blood purification
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 57
eISSN - 1421-9735
pISSN - 0253-5068
DOI - 10.1159/000232940
Subject(s) - pathophysiology , liver regeneration , proinflammatory cytokine , medicine , hepatocyte growth factor , hepatocyte , liver disease , immunology , liver failure , cytokine , chronic liver disease , inflammation , regeneration (biology) , biology , receptor , cirrhosis , microbiology and biotechnology , biochemistry , in vitro
This is the first ever decade which has witnessed the emergence of a highly lethal condition termed acute-on-chronic liver failure (ACLF), which today is the leading cause of death compared to acute and chronic liver failure. However, the complex pathophysiology of ACLF remains poorly understood. This article will attempt to summarize recent progress in the understanding of the mechanisms of cytokines in ACLF.
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