Open AccessInterleukin-8 and Acute Kidney Injury following Cardiopulmonary Bypass: A Prospective Cohort Study
Author(s) -
Orfeas Liangos,
Alexey Y. Kolyada,
Hocine Tighiouart,
Mary C. Perianayagam,
Ron Wald,
Bertrand L. Jaber
Publication year - 2009
Publication title -
nephron clinical practice
Language(s) - English
Resource type - Journals
ISSN - 1660-2110
DOI - 10.1159/000232595
Subject(s) - medicine , acute kidney injury , creatinine , cardiopulmonary bypass , prospective cohort study , perioperative , odds ratio , gastroenterology , cardiology , anesthesia
Cardiopulmonary bypass (CPB) elicits an inflammatory response mediated partly by neutrophils, which are activated and recruited by interleukin-8 (IL-8). We hypothesized that acute kidney injury (AKI) following CPB might be mediated by IL-8 and examined the association of perioperative plasma IL-8 levels with AKI in a prospective cohort.
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