Myosin Vc, a Member of the Actin Motor Family Associated with Rab8, Is Involved in the Release of DV2 from HepG2 Cells | Zendy

Xiao-Feng Xu | Zendy; Zongtao Chen | Zendy; Na Gao | Zendy; Junlei Zhang | Zendy; Jing An | Zendy

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Myosin Vc, a Member of the Actin Motor Family Associated with Rab8, Is Involved in the Release of DV2 from HepG2 Cells

Author(s) -

Xiao-Feng Xu,

Zongtao Chen,

Na Gao,

Junlei Zhang,

Jing An

Publication year - 2009

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000230669

Subject(s) - myosin , biology , actin , colocalization , microbiology and biotechnology , biophysics , transfection , cell culture , genetics

The pathogenesis of the dengue virus (DV) infection has not been well defined. We have reported that actin and Rab8 are involved in DV2 infection. Myosin Vc (Myo5c) is a novel member of the class V myosins and regulates the actin-mediated membrane trafficking associated with Rab8. In this study, the involvement of Myo5c in the release of DV2 was investigated in HpeG2 cells.

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