Antigenicity of Polypeptides (Poly Alpha Amino Acids) | Zendy

Paul H. Maurer | Zendy; Paul Pinchuck | Zendy; Bernard F. Gerulat | Zendy

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Antigenicity of Polypeptides (Poly Alpha Amino Acids)

Author(s) -

Paul H. Maurer,

Paul Pinchuck,

Bernard F. Gerulat

Publication year - 1967

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000229925

Subject(s) - antigenicity , precipitin , tyrosine , antigen , antibody , amino acid , adjuvant , chemistry , glutamic acid , biochemistry , biology , immunology

The ability of mice to form antibodies against the random terpolymer glu57lys38ala5 is controlled by a codominant Mendelian factor. Three of 7 inbred strains were 100 per cent responders; the others were completely negative. All of these strains could make antibody to related polymers with higher alanine content (10 and 40 mole per cent). Breeding studies using the progeny of Swiss mice indicated that a similar genetic factor was involved.

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