Gene-Gene Interaction between APOA5 and USF1: Two Candidate Genes for the Metabolic Syndrome | Zendy

Paula Singmann | Zendy; Jens Baumert | Zendy; Christian Herder | Zendy; Christa Meisinger | Zendy; Christina Holzapfel | Zendy; Norman Klopp | Zendy; H. E. Wichmann | Zendy; Martin Klingenspor | Zendy; Wolfgang Rathmann | Zendy; Thomas Illig | Zendy; Harald Grallert | Zendy

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Gene-Gene Interaction between <i>APOA5</i> and <i>USF1</i>: Two Candidate Genes for the Metabolic Syndrome

Author(s) -

Paula Singmann,

Jens Baumert,

Christian Herder,

Christa Meisinger,

Christina Holzapfel,

Norman Klopp,

H. E. Wichmann,

Martin Klingenspor,

Wolfgang Rathmann,

Thomas Illig,

Harald Grallert

Publication year - 2009

Publication title -

obesity facts

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.398

H-Index - 45

eISSN - 1662-4033

pISSN - 1662-4025

DOI - 10.1159/000227288

Subject(s) - medicine , gene , candidate gene , genetics , metabolic syndrome , endocrinology , biology , obesity

The metabolic syndrome, a major cluster of risk factors for cardiovascular diseases, shows increasing prevalence worldwide. Several studies have established associations of both apolipoprotein A5 (APOA5) gene variants and upstream stimulatory factor 1 (USF1) gene variants with blood lipid levels and metabolic syndrome. USF1 is a transcription factor for APOA5.

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