The Liver and Kidney in Critically Ill Patients | Zendy

Andrew Slack | Zendy; Julia Wendon | Zendy

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The Liver and Kidney in Critically Ill Patients

Author(s) -

Andrew Slack,

Julia Wendon

Publication year - 2009

Publication title -

blood purification

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.686

H-Index - 57

eISSN - 1421-9735

pISSN - 0253-5068

DOI - 10.1159/000227281

Subject(s) - hepatorenal syndrome , medicine , liver transplantation , intensive care medicine , liver disease , critically ill , kidney disease , vasopressin , transplantation , critical illness , renal replacement therapy , cirrhosis

Both liver and kidney dysfunction are associated with adverse outcomes in critical illness. Advanced liver disease can be complicated by the hepatorenal syndrome (HRS) with liver transplantation offering the best long-term outcome. However, until recently, HRS was associated with such a poor prognosis that this group of patients rarely survived long enough for transplantation to be considered. The use of vasopressin analogues and albumin infusions has improved the management of HRS and outcomes in terms of renal recovery and survival.

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